Glutathione
Glutathione (GSH) is an endogenous tripeptide composed of glutamate, cysteine, and glycine. Widely studied as the body’s master antioxidant, it plays a central role in redox homeostasis, oxidative stress mitigation, and Phase II detoxification pathway research models.
Key Functions & Benefits
- Detoxification: It is heavily utilized by the liver to bind with toxins and heavy metals, making them easier to excrete from the body. [1]
- Metabolic Health: Some clinical studies suggest it may help improve insulin sensitivity and mitigate cell damage in non-alcoholic fatty liver disease (MASLD). [1]
Increasing Glutathione Levels
While the body produces glutathione naturally, you can support its synthesis by eating sulfur-rich foods (e.g., broccoli, garlic, onions, and eggs) and getting adequate vitamins like folate and B12. [1]
Forms of Supplementation
Because oral glutathione is often broken down in the digestive tract before reaching the bloodstream, healthcare providers sometimes use alternative delivery methods. You can learn more about clinical applications through resources like the Healthline Overview of Glutathione or review medical definitions on the National Cancer Institute Drug Dictionary. [1, 2, 3]
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